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Catechin 7-O-beta-D-glucopyranoside
CAS No. 65597-47-9
Catechin 7-O-beta-D-glucopyranoside( —— )
Catalog No. M32494 CAS No. 65597-47-9
Catechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity.
Catechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCatechin 7-O-beta-D-glucopyranoside
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NoteResearch use only, not for human use.
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Brief DescriptionCatechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity.
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DescriptionCatechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity. Catechin 7-O-beta-D-glucopyranoside has a protective effect against STZ-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction.Catechin 7-O-β-D-glucopyranoside has strong inhibitory activity against α-amylase and α-glucosidase.Catechin 7-O-β-D-glucopyranoside has the activity of inhibiting protein glycation.
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In VitroCatechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction. Western Blot Analysis Cell Line:RINm5F rat pancreatic β-cells Concentration:10 μg/mL Incubation Time:24 hours Result:Increased the MnSOD level attenuated by Streptozotocin treatment.Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
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In VivoCatechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN.Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis. Animal Model:Mice injected with LPS/D-GalN Dosage:10 mg/kg Administration:Intraperitoneal injection; 10 mg/kg; once Result:Showed 80% LPS/DGalN-induced lethality in mice.Animal Model:Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis Dosage:10 mg/kg Administration:Oral administration; 10 mg/kg; once daily; 7 days Result:Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats.Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number65597-47-9
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Formula Weight452.4
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Molecular FormulaC21H24O11
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Purity>98% (HPLC)
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SolubilityDMSO, Pyridine, Methanol, Ethanol, etc.
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cell Biochem Funct . 2010 Dec 2;28(8):651-660.
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